An ultrasensitive impedance biosensor for Salmonella detection based on rotating high gradient magnetic separation and cascade reaction signal amplification

An impedance biosensor utilizing rotary magnetic separation and cascade reaction was developed for fast and ultrasensitive detection of Salmonella typhimurium. First, magnetic nanoparticles (MNPs) modified with anti-Salmonella monoclonal antibodies have been injected right into a capillary on the presence of a rotary high gradient magnetic area, which was rotated by a stepper motor. Then, a bacterial pattern

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